ABSTRACT
The objective of this study was to find the effects of herbal extract of tribulus terristris on the urine output and electrolytes in rabbits and to find a herbal remedy for fluid and electrolyte abnormalities. Descriptive. Department of Pharmacology and Therapeutics, Post Graduate Medical lnstitute, Lahore. The duration of study was for two weeks [in 2003]. Sixteen rabbits of mixed breed were purchased locally and kept in the animal house of Postgraduate Medical lnstitute, Lahore for a week for acclimatization before starting the experiment, Twelve hours light and dark cycle was maintained. They were fed on grass, grain, seasonal vegetables and water adlibitum. Animals were weighed for calculation of dosage of herb.
ABSTRACT
To study the effect of tribulus terristris on urinary pH, uric acid and calcium as a herbal diuretic agent. Descriptive study. The study was conducted postgraduate medical institute [PGMI] Lahore and duration of study was two weeks. Tribulus terristris extract [100 mg/kg body weight] was administered in rabbits. Rabbits are divided into two groups CT and Tt. There were significant alkalinization of urine and significant reduction in urinary uric acid level and insignificant urinary calcium level observed. It is concluded that alkalinization and reduction of urinary uric acid by Tt would be helpful to reduce renal stone formation